ABSTRACT
Control of MRSA in hospital is essential. It can be achieved by proper implementation of hospital infection control measures, regular surveillance activity and selecting the right antibiotic is an important determinant of clinical outcome in such cases. Present paper deals with the antibiotics prescribing pattern for MRSA infections by doctors, which can be used to monitor the geographical spread and the selection pressure resulting from antibiotic usage. Material & Methods: For this study, a questionnaire was prepared which include list of antibiotics used for treatment of MRSA. A total of 83 doctors were surveyed, responses were received by 76 (91.6%) physicians (68 hospital setting or working in the hospital and 8 were skin specialist). Results: The vancomycin, an intravenous drug, was the most prescribed drug (53.9%). The amoxycillin+ calvulanic acid (Augmentin) and piperacillin+ tazobactum (Zosyn) were prescribed by physicians (53.9%) and (27.6%) respectively. Other cephalosporins (with or without sublactam combination) and carbapenems were prescribed by less than 20% doctors. The linezolid is next drug that was recommended by doctors (38.2%). Other drugs were prescribed by less than 20% of physicians which include amikacin, gentamicin, erythromycin, clarithromycin, levofloxacin, ofloxacin, ciprofloxacin, gatifloxacin, quinupristin-dalfopristin, clindamycin and rifampin. Mupirocin was prescribed by 4.5% of physicians. Conclusions: In conclusion, vancomycin remains a first-choice of drug by physicians for severe infections possibly caused by MRSA. As per them, other antibiotic agents may be appropriate to consider in some circumstances. Combination of â-lactam antibiotics, macrolides and aminoglycosides was generally to cover other gram-positive and/or gram-negative, aerobic and anaerobic organisms.